OSTEOARTHRITIS IN VITRO MODELS: APPLICATIONS AND IMPLICATIONS IN DEVELOPMENT OF INTRA-ARTICULAR DRUG DELIVERY SYSTEMS

Osteoarthritis In Vitro Models: Applications and Implications in Development of Intra-Articular Drug Delivery Systems

Osteoarthritis (OA) is a complex multi-target disease with an unmet medical need for the development of therapies that slow and potentially revert disease progression.Intra-articular (IA) delivery has seen a surge in osteoarthritis research in recent years.As local administration of molecules, this represents a way to circumvent systemic drug deliv

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Environmental enrichment for primates in laboratories

Environmental enrichment is a critical component of Refinement, one of the 3Rs underlying humane experimentation on animals.In this paper I discuss why primates housed in laboratories, which often have constraints of space and study protocols, are a special case for enrichment.I outline a framework for categorising the different types Deodorant of

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Ambiguity attacks on robust blind image watermarking scheme based on redundant discrete wavelet transform and singular value decomposition

Among emergent applications of digital watermarking are copyright protection and proof of ownership.Recently, Makbol and Khoo (2013) have proposed for these applications a new robust Engine Pulleys blind image watermarking scheme based on the redundant discrete wavelet transform (RDWT) and the singular value decomposition (SVD).In this paper, we pr

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